tert-butyl 7-bromoindoline-1-carboxylate

tert-butyl 7-bromoindoline-1-carboxylate - Names and Identifiers

Name	7-BROMO-2,3-DIHYDRO-INDOLE-1-CARBOXYLIC ACID TERT-BUTYL ESTER
Synonyms	BOC-7-BROMOINDOLINE N-Boc-7-bromoindoline 1-Boc-7-bromoindoline 7-broMo-N-Boc-indoline tert-butyl 7-bromoindoline-1-carboxylate tert-butyl 7-bromo-2,3-dihydro-1H-indole-1-carboxylate 7-BROMO-2,3-DIHYDRO-INDOLE-1-CARBOXYLIC ACID TERT-BUTYL ESTER 7-BROMO-2,3-DIHYDRO-INDOLE-1-CARBOXYLIC ACID TERT-BUTYL ESTE... 1H-Indole-1-carboxylicacid, 7-broMo-2,3-dihydro-, 1,1-diMethylethyl ester
CAS	143262-17-3
InChI	InChI=1/C13H16BrNO2/c1-13(2,3)17-12(16)15-8-7-9-5-4-6-10(14)11(9)15/h4-6H,7-8H2,1-3H3

tert-butyl 7-bromoindoline-1-carboxylate - Physico-chemical Properties

Molecular Formula	C13H16BrNO2
Molar Mass	298.18
Density	1.4g/cm³
Boling Point	349.9°C at 760 mmHg
Flash Point	165.4°C
Vapor Presure	4.55E-05mmHg at 25°C
Storage Condition	2-8°C
Refractive Index	1.57

tert-butyl 7-bromoindoline-1-carboxylate - Introduction

N-Boc-7-bromoindoline is an organic compound with the following properties:

Appearance: Usually a white solid.
molecular formula: C12H15BrNO2.
Molecular weight: 290.16g/mol.

N-Boc-7-bromoindoline has a wide range of applications in organic synthesis. It is an important intermediate commonly used in the preparation of amphetamine-like compounds, such as the antipsychotic drug olanzapine. In addition, it can also be used to synthesize other organic compounds of similar structure, expanding the field of chemical research and application.

The preparation method of N-Boc-7-bromoindoline generally comprises the following steps: reacting 7-bromoindoline with N-Boc-oxamic acid to generate the target product. For specific synthetic procedures, reference may be made to organic synthesis literature or synthetic manuals.

It is important to note the safety information when using N-Boc-7-bromoindoline. Because it is an organic bromine compound, it has certain toxicity and irritation. During operation, it is necessary to wear suitable protective equipment, such as gloves and goggles, to prevent contact with skin or eyes. In addition, during storage and disposal, it is necessary to follow relevant safety procedures, such as avoiding exposure to fire and avoiding contact with strong oxidizing agents.

Last Update：2024-04-09 21:04:16